ACTG2
Gene Information
- Official Symbol: ACTG2
- Official Name: actin gamma 2, smooth muscle
- Aliases and Previous Symbols: N/A
- Entrez ID: 72
- UniProt: P63267
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010].
- UniProt Summary: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 2539
- Expression level (log2 read counts): 1.74
ACTG2 Expression in NALM6 Cells: 1.74
