UniProt Summary: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). {ECO:0000269|PubMed:10448098, ECO:0000303|PubMed:10333475, ECO:0000305}.
Pfam DomainsGO Terms
Pfam Domains
PH
ArfGap
GO Terms
inositol 1,3,4,5 tetrakisphosphate binding
phosphatidylinositol bisphosphate binding
phosphatidylinositol-3,4,5-trisphosphate binding
GTPase activator activity
positive regulation of GTPase activity
regulation of GTPase activity
positive regulation of hydrolase activity
regulation of hydrolase activity
positive regulation of catalytic activity
positive regulation of molecular function
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)