Pfam Domains GO Terms
| ADH N |
| ADH zinc N |
| benzaldehyde dehydrogenase activity |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| S-(hydroxymethyl)glutathione dehydrogenase activity |
| all-trans retinal binding |
| ethanol binding |
| formaldehyde catabolic process |
| NADPH:quinone reductase activity |
| formaldehyde metabolic process |
| alcohol dehydrogenase (NAD) activity |
| cellular detoxification of aldehyde |
| alcohol dehydrogenase activity, zinc-dependent |
| cellular response to aldehyde |
| aldehyde catabolic process |
| ethanol oxidation |
| alditol:NADP+ 1-oxidoreductase activity |
| retinol binding |
| retinol dehydrogenase activity |
| ethanol metabolic process |
| quinone metabolic process |
| NAD binding |
| retinol metabolic process |
| antibiotic catabolic process |
| cellular aldehyde metabolic process |
| alcohol catabolic process |
| cellular ketone metabolic process |
| organic hydroxy compound catabolic process |
| primary alcohol metabolic process |
| cellular detoxification |
| antibiotic metabolic process |
| retinoid metabolic process |
| diterpenoid metabolic process |
| terpenoid metabolic process |
| cellular hormone metabolic process |
| detoxification |
| isoprenoid metabolic process |
| hormone metabolic process |
| cellular response to toxic substance |
| alcohol metabolic process |
| generation of precursor metabolites and energy |
| small molecule catabolic process |
| cofactor metabolic process |
| organic hydroxy compound metabolic process |
| drug metabolic process |
| response to toxic substance |
| regulation of hormone levels |
| zinc ion binding |
| cellular lipid metabolic process |
| oxidation-reduction process |
| cellular response to oxygen-containing compound |
| lipid metabolic process |
| response to oxygen-containing compound |
| small molecule metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution