ALG10
Gene Information
- Official Symbol: ALG10
- Official Name: ALG10 alpha-1,2-glucosyltransferase
- Aliases and Previous Symbols: N/A
- Entrez ID: 84920
- UniProt: Q5BKT4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010].
- UniProt Summary: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 18387
- Expression level (log2 read counts): 4.68
ALG10 Expression in NALM6 Cells: 4.68
