UniProt Summary: Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. {ECO:0000269|PubMed:25407797}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
positive regulation of enamel mineralization
positive regulation of odontogenesis of dentin-containing tooth
regulation of enamel mineralization
positive regulation of tooth mineralization
regulation of tooth mineralization
positive regulation of odontogenesis
regulation of odontogenesis of dentin-containing tooth
regulation of odontogenesis
positive regulation of biomineral tissue development
positive regulation of biomineralization
positive regulation of animal organ morphogenesis
odontogenesis of dentin-containing tooth
basement membrane
regulation of biomineralization
biomineralization
regulation of biomineral tissue development
biomineral tissue development
odontogenesis
cell-cell junction
extracellular matrix
regulation of animal organ morphogenesis
endoplasmic reticulum lumen
post-translational protein modification
molecular function
cell adhesion
biological adhesion
animal organ morphogenesis
regulation of anatomical structure morphogenesis
positive regulation of developmental process
positive regulation of multicellular organismal process
tissue development
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739