Pfam Domains GO Terms
| Annexin |
| negative regulation of phospholipase A2 activity |
| negative regulation of serine-type peptidase activity |
| negative regulation of serine-type endopeptidase activity |
| negative regulation of phospholipase activity |
| regulation of serine-type endopeptidase activity |
| regulation of serine-type peptidase activity |
| regulation of phospholipase A2 activity |
| negative regulation of lipase activity |
| phosphatidylinositol-3,4-bisphosphate binding |
| phosphatidylinositol-3,4,5-trisphosphate binding |
| calcium-dependent phospholipid binding |
| regulation of phospholipase activity |
| phosphatidylinositol-4,5-bisphosphate binding |
| endosome organization |
| regulation of lipase activity |
| late endosome membrane |
| actin filament binding |
| endosomal transport |
| negative regulation of endopeptidase activity |
| negative regulation of peptidase activity |
| blood coagulation |
| coagulation |
| hemostasis |
| vesicle organization |
| negative regulation of proteolysis |
| collagen-containing extracellular matrix |
| regulation of endopeptidase activity |
| endomembrane system organization |
| regulation of peptidase activity |
| negative regulation of hydrolase activity |
| wound healing |
| regulation of body fluid levels |
| response to wounding |
| calcium ion binding |
| regulation of proteolysis |
| negative regulation of catalytic activity |
| negative regulation of cellular protein metabolic process |
| negative regulation of protein metabolic process |
| negative regulation of molecular function |
| regulation of hydrolase activity |
| intracellular transport |
| establishment of localization in cell |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Cannabidiol 13μM R08 exp465 | 1.87 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution