Entrez Summary: This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
ApoL
GO Terms
high-density lipoprotein particle binding
acute-phase response
maternal process involved in female pregnancy
acute inflammatory response
cholesterol metabolic process
lipoprotein metabolic process
secondary alcohol metabolic process
sterol metabolic process
lipid binding
female pregnancy
multi-multicellular organism process
steroid metabolic process
lipid transport
alcohol metabolic process
lipid localization
signaling receptor binding
organic hydroxy compound metabolic process
inflammatory response
multicellular organismal reproductive process
multicellular organism reproduction
endoplasmic reticulum membrane
multi-organism reproductive process
lipid metabolic process
defense response
reproductive process
reproduction
small molecule metabolic process
extracellular region
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739