ARHGDIG

• Official Symbol: ARHGDIG
• Official Name: Rho GDP dissociation inhibitor gamma
• Aliases and Previous Symbols: N/A
• Entrez ID: 398
• UniProt: Q99819
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 14927
• Expression level (log2 read counts): -1.01

Expression Distribution

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ARHGDIG Expression in NALM6 Cells: -1.01