ARL4A
Gene Information
- Official Symbol: ARL4A
- Official Name: ADP ribosylation factor like GTPase 4A
- Aliases and Previous Symbols: N/A
- Entrez ID: 10124
- UniProt: P40617
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. {ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 10692
- Expression level (log2 read counts): 0.56
ARL4A Expression in NALM6 Cells: 0.56
