ATAD2

• Official Symbol: ATAD2
• Official Name: ATPase family AAA domain containing 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 29028
• UniProt: Q6PL18
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. {ECO:0000269|PubMed:17998543}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 15270
• Expression level (log2 read counts): 8.46

Expression Distribution

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ATAD2 Expression in NALM6 Cells: 8.46