ATCAY
Gene Information
- Official Symbol: ATCAY
- Official Name: ATCAY kinesin light chain interacting caytaxin
- Aliases and Previous Symbols: N/A
- Entrez ID: 85300
- UniProt: Q86WG3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008].
- UniProt Summary: Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites. {ECO:0000269|PubMed:16899818}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 9325
- Expression level (log2 read counts): 4.25
ATCAY Expression in NALM6 Cells: 4.25
