BDP1
Gene Information
- Official Symbol: BDP1
- Official Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
- Aliases and Previous Symbols: N/A
- Entrez ID: 55814
- UniProt: A6H8Y1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5084
- Expression level (log2 read counts): 7.7
BDP1 Expression in NALM6 Cells: 7.7
