UniProt Summary: Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). {ECO:0000250|UniProtKB:O35152}.
Pfam DomainsGO Terms
Pfam Domains
SNARE
GO Terms
regulation of retrograde vesicle-mediated transport, Golgi to ER
Golgi trans cisterna
SNAP receptor activity
SNARE complex
integral component of Golgi membrane
retrograde transport, endosome to Golgi
membrane fusion
cytosolic transport
endoplasmic reticulum to Golgi vesicle-mediated transport
endosomal transport
endosome
Golgi vesicle transport
regulation of vesicle-mediated transport
Golgi membrane
membrane organization
Golgi apparatus
protein transport
intracellular transport
peptide transport
amide transport
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
regulation of transport
vesicle-mediated transport
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739