Pfam Domains GO Terms
| positive regulation of urine volume |
| regulation of urine volume |
| ERBB2 signaling pathway |
| epidermal growth factor receptor binding |
| negative regulation of epidermal growth factor receptor signaling pathway |
| epidermal growth factor receptor signaling pathway |
| positive regulation of fibroblast proliferation |
| negative regulation of ERBB signaling pathway |
| clathrin-coated vesicle membrane |
| positive regulation of mitotic nuclear division |
| positive regulation of nuclear division |
| ERBB signaling pathway |
| regulation of fibroblast proliferation |
| regulation of epidermal growth factor receptor signaling pathway |
| positive regulation of cell division |
| regulation of ERBB signaling pathway |
| renal system process |
| positive regulation of mitotic cell cycle |
| growth factor activity |
| positive regulation of protein kinase B signaling |
| regulation of mitotic nuclear division |
| regulation of cell division |
| regulation of nuclear division |
| regulation of protein kinase B signaling |
| positive regulation of cell cycle process |
| MAPK cascade |
| positive regulation of cell cycle |
| signal transduction by protein phosphorylation |
| regulation of body fluid levels |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| positive regulation of organelle organization |
| regulation of mitotic cell cycle |
| enzyme linked receptor protein signaling pathway |
| regulation of cell cycle process |
| membrane organization |
| negative regulation of apoptotic process |
| negative regulation of programmed cell death |
| regulation of cell motility |
| positive regulation of cell population proliferation |
| positive regulation of cell differentiation |
| protein phosphorylation |
| regulation of locomotion |
| negative regulation of cell death |
| regulation of cellular component movement |
| positive regulation of intracellular signal transduction |
| regulation of cell cycle |
| positive regulation of cellular component organization |
| negative regulation of signal transduction |
| phosphorylation |
| regulation of organelle organization |
| negative regulation of cell communication |
| negative regulation of signaling |
| positive regulation of developmental process |
| regulation of apoptotic process |
| regulation of programmed cell death |
| extracellular space |
| regulation of cell population proliferation |
| negative regulation of response to stimulus |
| positive regulation of signal transduction |
| regulation of cell death |
| intracellular signal transduction |
| regulation of cell differentiation |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| extracellular region |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| RK-33 8μM R08 exp518 | -1.87 |
| Sulforaphane 9μM R08 exp526 no dilution day6 | 2 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution