UniProt Summary: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. {ECO:0000269|PubMed:18703501}.
Pfam DomainsGO Terms
Pfam Domains
Carb anhydrase
GO Terms
carbonate dehydratase activity
microvillus membrane
response to testosterone
bicarbonate transport
regulation of transcription from RNA polymerase II promoter in response to hypoxia
regulation of transcription from RNA polymerase II promoter in response to stress
regulation of DNA-templated transcription in response to stress
cellular response to hypoxia
response to ketone
basolateral plasma membrane
cellular response to decreased oxygen levels
cellular response to oxygen levels
response to hypoxia
response to decreased oxygen levels
response to oxygen levels
morphogenesis of an epithelium
organic anion transport
tissue morphogenesis
anion transport
zinc ion binding
response to lipid
nucleolus
response to hormone
response to organic cyclic compound
response to drug
epithelium development
secretion
response to abiotic stimulus
ion transport
response to endogenous stimulus
response to oxygen-containing compound
cellular response to stress
tissue development
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)