Pfam Domains GO Terms
| negative regulation of granulocyte macrophage colony-stimulating factor production |
| negative regulation of interleukin-18 production |
| negative regulation of mast cell degranulation |
| regulation of interleukin-18 production |
| negative regulation of mast cell activation involved in immune response |
| negative regulation of myeloid leukocyte mediated immunity |
| negative regulation of leukocyte degranulation |
| negative regulation of mast cell activation |
| regulation of store-operated calcium entry |
| regulation of granulocyte macrophage colony-stimulating factor production |
| negative regulation of regulated secretory pathway |
| negative regulation of exocytosis |
| regulation of mast cell degranulation |
| regulation of mast cell activation involved in immune response |
| regulation of mast cell activation |
| regulation of leukocyte degranulation |
| negative regulation of leukocyte mediated immunity |
| regulation of myeloid leukocyte mediated immunity |
| negative regulation of intracellular transport |
| negative regulation of immune effector process |
| negative regulation of immune response |
| regulation of regulated secretory pathway |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| negative regulation of leukocyte activation |
| negative regulation of cell activation |
| negative regulation of secretion by cell |
| regulation of leukocyte mediated immunity |
| positive regulation of immune effector process |
| regulation of exocytosis |
| negative regulation of secretion |
| regulation of calcium ion transport |
| cell-cell adhesion via plasma-membrane adhesion molecules |
| process utilizing autophagic mechanism |
| autophagy |
| negative regulation of cytokine production |
| regulation of intracellular transport |
| leukocyte migration |
| regulation of metal ion transport |
| negative regulation of immune system process |
| regulation of immune effector process |
| negative regulation of transport |
| cell-cell adhesion |
| regulation of vesicle-mediated transport |
| regulation of leukocyte activation |
| adaptive immune response |
| regulation of cell activation |
| regulation of cytokine production |
| regulation of ion transport |
| regulation of secretion by cell |
| innate immune response |
| regulation of secretion |
| regulation of cellular localization |
| cell adhesion |
| biological adhesion |
| defense response to other organism |
| cell migration |
| identical protein binding |
| cell motility |
| localization of cell |
| positive regulation of immune system process |
| regulation of immune response |
| negative regulation of multicellular organismal process |
| response to other organism |
| response to external biotic stimulus |
| locomotion |
| response to biotic stimulus |
| defense response |
| integral component of plasma membrane |
| movement of cell or subcellular component |
| negative regulation of response to stimulus |
| regulation of immune system process |
| cellular catabolic process |
| regulation of transport |
| immune response |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution