UniProt Summary: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Pfam DomainsGO Terms
Pfam Domains
Cadherin
GO Terms
cell-cell adhesion mediated by cadherin
catenin complex
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
virus receptor activity
cytoskeletal protein binding
adherens junction organization
viral entry into host cell
entry into host
entry into host cell
cell-cell adherens junction
cell-cell junction assembly
cell-cell junction organization
interaction with host
cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules
viral life cycle
cell junction organization
cell-cell adhesion via plasma-membrane adhesion molecules
cadherin binding
cell-cell adhesion
cell surface
viral process
calcium ion binding
cell morphogenesis
symbiotic process
interspecies interaction between organisms
cellular component morphogenesis
protein homodimerization activity
cell adhesion
biological adhesion
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739