UniProt Summary: Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response. {ECO:0000250|UniProtKB:Q9D2Z1}.
Pfam DomainsGO Terms
Pfam Domains
ig
I-set
GO Terms
microvillus membrane
apical plasma membrane
positive regulation of cytokine production
response to bacterium
regulation of cytokine production
response to other organism
response to external biotic stimulus
response to biotic stimulus
positive regulation of multicellular organismal process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)