UniProt Summary: Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis. {ECO:0000269|PubMed:18772885}.
Pfam DomainsGO Terms
Pfam Domains
GFA
GO Terms
pericentric heterochromatin assembly
carbon-sulfur lyase activity
heterochromatin assembly
heterochromatin organization
spindle midzone
chromatin remodeling at centromere
centromere complex assembly
positive regulation of cytokinesis
kinetochore
positive regulation of cell division
regulation of cytokinesis
condensed chromosome kinetochore
chromatin assembly
microtubule cytoskeleton
chromatin assembly or disassembly
chromatin remodeling
regulation of cell division
ameboidal-type cell migration
DNA packaging
protein-DNA complex assembly
protein-DNA complex subunit organization
positive regulation of cell cycle process
DNA conformation change
regulation of chromosome organization
positive regulation of cell cycle
cell division
chromatin organization
regulation of cell cycle process
molecular function
cellular protein-containing complex assembly
cell migration
chromosome organization
localization of cell
cell motility
regulation of cell cycle
regulation of organelle organization
locomotion
cell cycle
movement of cell or subcellular component
protein-containing complex assembly
protein-containing complex subunit organization
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)