CHIA
Gene Information
- Official Symbol: CHIA
- Official Name: chitinase acidic
- Aliases and Previous Symbols: N/A
- Entrez ID: 27159
- UniProt: Q9BZP6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| CBM 14 |
| Glyco hydro 18 |
GO Terms
| chitin metabolic process |
| chitin catabolic process |
| chitinase activity |
| polysaccharide digestion |
| glucosamine-containing compound catabolic process |
| chitin binding |
| amino sugar catabolic process |
| positive regulation of chemokine secretion |
| regulation of chemokine secretion |
| production of molecular mediator involved in inflammatory response |
| polysaccharide catabolic process |
| glucosamine-containing compound metabolic process |
| amino sugar metabolic process |
| positive regulation of chemokine production |
| aminoglycan catabolic process |
| regulation of chemokine production |
| polysaccharide metabolic process |
| kinase binding |
| digestion |
| carbohydrate catabolic process |
| positive regulation of cytokine secretion |
| drug catabolic process |
| aminoglycan metabolic process |
| carbohydrate derivative catabolic process |
| regulation of cytokine secretion |
| positive regulation of protein secretion |
| positive regulation of peptide secretion |
| positive regulation of secretion by cell |
| positive regulation of protein transport |
| positive regulation of secretion |
| positive regulation of cytokine production |
| positive regulation of establishment of protein localization |
| regulation of protein secretion |
| carbohydrate metabolic process |
| regulation of peptide secretion |
| inflammatory response |
| drug metabolic process |
| regulation of cytokine production |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of secretion |
| apoptotic process |
| positive regulation of transport |
| carbohydrate derivative metabolic process |
| regulation of protein localization |
| macromolecule catabolic process |
| programmed cell death |
| organonitrogen compound catabolic process |
| cell death |
| defense response |
| extracellular space |
| positive regulation of multicellular organismal process |
| organic substance catabolic process |
| cellular catabolic process |
| regulation of transport |
| extracellular region |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Actinomycin-D 0.001μM R00 exp3 | 1.8 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12416
- Expression level (log2 read counts): -1.52
Expression Distribution
CHIA Expression in NALM6 Cells: -1.52
