CLTCL1
Gene Information
- Official Symbol: CLTCL1
- Official Name: clathrin heavy chain like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 8218
- UniProt: P53675
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
- UniProt Summary: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16514
- Expression level (log2 read counts): 4.15
CLTCL1 Expression in NALM6 Cells: 4.15
