UniProt Summary: Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine (PubMed:10224141). Acts as a chemoattractant, probably involved in the regulation of cell migration (PubMed:28301481). {ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}.
Pfam DomainsGO Terms
Pfam Domains
Lectin C
Collagen
GO Terms
complement activation, lectin pathway
monosaccharide binding
mannose binding
chemoattractant activity
positive chemotaxis
collagen trimer
cranial skeletal system development
complement activation
humoral immune response
chemotaxis
taxis
activation of immune response
innate immune response
positive regulation of immune response
defense response to other organism
Golgi apparatus
immune effector process
positive regulation of immune system process
regulation of immune response
response to other organism
response to external biotic stimulus
locomotion
response to biotic stimulus
defense response
extracellular space
regulation of immune system process
immune response
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)