UniProt Summary: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Pfam DomainsGO Terms
Pfam Domains
COX6A
GO Terms
mitochondrial respiratory chain complex IV
enzyme regulator activity
mitochondrial electron transport, cytochrome c to oxygen
aerobic electron transport chain
cytochrome-c oxidase activity
aerobic respiration
mitochondrial ATP synthesis coupled electron transport
ATP synthesis coupled electron transport
respiratory electron transport chain
oxidative phosphorylation
proton transmembrane transport
cellular respiration
electron transport chain
ATP metabolic process
energy derivation by oxidation of organic compounds
monovalent inorganic cation transport
generation of precursor metabolites and energy
inorganic cation transmembrane transport
cation transmembrane transport
inorganic ion transmembrane transport
cation transport
ion transmembrane transport
oxidation-reduction process
transmembrane transport
phosphorylation
ion transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739