CSF3R
Gene Information
- Official Symbol: CSF3R
- Official Name: colony stimulating factor 3 receptor
- Aliases and Previous Symbols: N/A
- Entrez ID: 1441
- UniProt: Q99062
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010].
- UniProt Summary: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. {ECO:0000269|PubMed:7514305}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8429
- Expression level (log2 read counts): 1.89
CSF3R Expression in NALM6 Cells: 1.89
