CSPP1
Gene Information
- Official Symbol: CSPP1
- Official Name: centrosome and spindle pole associated protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 79848
- UniProt: Q1MSJ5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014].
- UniProt Summary: May play a role in cell-cycle-dependent microtubule organization. {ECO:0000269|PubMed:16826565}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14919
- Expression level (log2 read counts): 6.17
CSPP1 Expression in NALM6 Cells: 6.17
