CTCFL
Gene Information
- Official Symbol: CTCFL
- Official Name: CCCTC-binding factor like
- Aliases and Previous Symbols: N/A
- Entrez ID: 140690
- UniProt: Q8NI51
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| regulation of gene expression by genetic imprinting |
| DNA methylation involved in gamete generation |
| genetic imprinting |
| regulation of histone H3-K4 methylation |
| DNA methylation |
| DNA alkylation |
| DNA methylation or demethylation |
| regulation of histone methylation |
| DNA modification |
| histone methylation |
| histone binding |
| protein alkylation |
| protein methylation |
| regulation of histone modification |
| regulation of chromatin organization |
| transcription regulatory region DNA binding |
| regulation of gene expression, epigenetic |
| macromolecule methylation |
| methylation |
| regulation of chromosome organization |
| cellular process involved in reproduction in multicellular organism |
| histone modification |
| covalent chromatin modification |
| sequence-specific DNA binding |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| gamete generation |
| chromatin organization |
| DNA metabolic process |
| multicellular organismal reproductive process |
| sexual reproduction |
| multicellular organism reproduction |
| multi-organism reproductive process |
| chromosome organization |
| positive regulation of transcription by RNA polymerase II |
| regulation of organelle organization |
| cell cycle |
| reproductive process |
| reproduction |
| DNA binding |
| positive regulation of transcription, DNA-templated |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| positive regulation of RNA metabolic process |
| regulation of protein modification process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Q15 1 to 2μM on day4 R04 exp164 | -1.76 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 11796
- Expression level (log2 read counts): 3.56
Expression Distribution
CTCFL Expression in NALM6 Cells: 3.56
