Pfam Domains GO Terms
| Trypsin |
| neutrophil mediated killing of gram-positive bacterium |
| neutrophil mediated killing of bacterium |
| neutrophil mediated killing of symbiont cell |
| neutrophil mediated cytotoxicity |
| killing by host of symbiont cells |
| disruption by host of symbiont cells |
| angiotensin maturation |
| killing of cells in other organism involved in symbiotic interaction |
| regulation of angiotensin levels in blood |
| disruption of cells of other organism involved in symbiotic interaction |
| regulation of systemic arterial blood pressure by circulatory renin-angiotensin |
| regulation of systemic arterial blood pressure by renin-angiotensin |
| peptide hormone processing |
| regulation of systemic arterial blood pressure by hormone |
| defense response to fungus |
| antibacterial humoral response |
| leukocyte mediated cytotoxicity |
| regulation of systemic arterial blood pressure mediated by a chemical signal |
| endocrine process |
| response to fungus |
| disruption of cells of other organism |
| killing of cells of other organism |
| serine-type peptidase activity |
| extracellular matrix disassembly |
| cytoplasmic stress granule |
| modification by host of symbiont morphology or physiology |
| interaction with symbiont |
| peptidase activity |
| defense response to Gram-negative bacterium |
| secretory granule |
| cell killing |
| azurophil granule lumen |
| defense response to Gram-positive bacterium |
| regulation of systemic arterial blood pressure |
| modification of morphology or physiology of other organism involved in symbiotic interaction |
| antimicrobial humoral response |
| modification of morphology or physiology of other organism |
| protein processing |
| serine-type endopeptidase activity |
| heparin binding |
| regulation of blood pressure |
| cellular response to lipopolysaccharide |
| cellular response to molecule of bacterial origin |
| hormone metabolic process |
| cellular response to biotic stimulus |
| protein maturation |
| response to lipopolysaccharide |
| response to molecule of bacterial origin |
| defense response to bacterium |
| extracellular matrix organization |
| humoral immune response |
| collagen-containing extracellular matrix |
| extracellular structure organization |
| blood circulation |
| circulatory system process |
| cellular component disassembly |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| cellular response to lipid |
| myeloid cell activation involved in immune response |
| peptide metabolic process |
| regulation of hormone levels |
| myeloid leukocyte activation |
| cell surface |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| response to bacterium |
| regulated exocytosis |
| leukocyte mediated immunity |
| symbiotic process |
| cellular amide metabolic process |
| exocytosis |
| interspecies interaction between organisms |
| response to lipid |
| positive regulation of immune response |
| leukocyte activation |
| defense response to other organism |
| protein phosphorylation |
| secretion by cell |
| export from cell |
| cellular response to oxygen-containing compound |
| cell activation |
| immune effector process |
| secretion |
| regulation of immune response |
| positive regulation of immune system process |
| proteolysis |
| phosphorylation |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| response to oxygen-containing compound |
| extracellular space |
| regulation of immune system process |
| immune response |
| extracellular region |
| vesicle-mediated transport |
| system process |
| gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution