UniProt Summary: ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). {ECO:0000250, ECO:0000269|PubMed:10608860}.
Pfam DomainsGO Terms
Pfam Domains
Helicase C
DEAD
GO Terms
chromatoid body
poly(A)+ mRNA export from nucleus
RNA helicase activity
cytoplasmic stress granule
mRNA export from nucleus
mRNA-containing ribonucleoprotein complex export from nucleus
ribonucleoprotein complex export from nucleus
ribonucleoprotein complex localization
RNA export from nucleus
protein export from nucleus
spermatid development
mRNA transport
spermatid differentiation
nuclear export
nucleic acid transport
RNA transport
establishment of RNA localization
RNA localization
nucleobase-containing compound transport
protein-containing complex localization
germ cell development
nucleocytoplasmic transport
nuclear transport
regulation of translation
cellular process involved in reproduction in multicellular organism
regulation of cellular amide metabolic process
posttranscriptional regulation of gene expression
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
intracellular protein transport
RNA binding
reproductive process
reproduction
ATP binding
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cell development
establishment of localization in cell
nitrogen compound transport
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)