Pfam Domains GO Terms
| DEAD |
| Helicase C |
| piRNA biosynthetic process |
| piP-body |
| pi-body |
| P granule |
| piRNA metabolic process |
| DNA methylation involved in gamete generation |
| regulation of transposition |
| negative regulation of transposition |
| male meiosis I |
| DNA methylation |
| DNA alkylation |
| male meiotic nuclear division |
| RNA helicase activity |
| DNA methylation or demethylation |
| flagellated sperm motility |
| sperm motility |
| gene silencing by RNA |
| DNA modification |
| cilium-dependent cell motility |
| cilium or flagellum-dependent cell motility |
| meiosis I |
| meiosis I cell cycle process |
| gene silencing |
| meiotic nuclear division |
| meiotic cell cycle process |
| nucleic acid binding |
| meiotic cell cycle |
| ATPase activity |
| macromolecule methylation |
| nuclear division |
| organelle fission |
| methylation |
| cellular process involved in reproduction in multicellular organism |
| ncRNA metabolic process |
| spermatogenesis |
| male gamete generation |
| gamete generation |
| perinuclear region of cytoplasm |
| DNA metabolic process |
| multicellular organismal reproductive process |
| sexual reproduction |
| multicellular organism reproduction |
| multi-organism reproductive process |
| cell cycle process |
| cell motility |
| localization of cell |
| locomotion |
| cell cycle |
| RNA binding |
| reproductive process |
| reproduction |
| ATP binding |
| movement of cell or subcellular component |
| RNA metabolic process |
| negative regulation of gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Sulforaphane 9μM R08 exp526 no dilution day6 | -1.76 |
| Metformin 100 to 150μM on day4 R04 exp170 | 1.81 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution