UniProt Summary: Has antibacterial activity (PubMed:12600824). Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:23938203). {ECO:0000269|PubMed:12600824, ECO:0000269|PubMed:23938203}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
microvesicle
antifungal innate immune response
CCR2 chemokine receptor binding
lipopolysaccharide binding
defense response to fungus
response to fungus
extrinsic component of membrane
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
heparin binding
defense response to bacterium
response to bacterium
innate immune response
defense response to other organism
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
immune response
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739