DHX16

Entrez Summary: N/A
UniProt Summary: Involved in pre-mRNA splicing. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. {ECO:0000269|PubMed:20423332, ECO:0000269|PubMed:20841358, ECO:0000269|PubMed:25296192}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Atovaquone 15μM R08 exp451	-1.77
RK-33 8μM R08 exp518	1.89

Global Fraction of Cell Lines Where Essential: 115/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	6/28
blood	1/28
bone	5/26
breast	5/33
central nervous system	6/56
cervix	0/4
colorectal	5/17
esophagus	3/13
fibroblast	0/1
gastric	1/16
kidney	4/21
liver	4/20
lung	14/75
lymphocyte	2/16
ovary	4/26
pancreas	4/24
peripheral nervous system	1/16
plasma cell	1/15
prostate	0/1
skin	3/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	4/22
urinary tract	3/29
uterus	1/5

Expression Distribution