Pfam Domains GO Terms
| DM |
| positive regulation of histone H3-K9 dimethylation |
| spermatid nucleus elongation |
| regulation of histone H3-K9 dimethylation |
| positive regulation of histone H3-K9 trimethylation |
| regulation of histone H3-K9 trimethylation |
| positive regulation of histone H3-K9 methylation |
| XY body |
| spermatid nucleus differentiation |
| regulation of histone H3-K9 methylation |
| male meiosis I |
| positive regulation of histone methylation |
| male meiotic nuclear division |
| regulation of histone methylation |
| positive regulation of histone modification |
| positive regulation of chromatin organization |
| meiosis I |
| meiosis I cell cycle process |
| nucleus organization |
| regulation of histone modification |
| spermatid development |
| meiotic nuclear division |
| spermatid differentiation |
| meiotic cell cycle process |
| positive regulation of chromosome organization |
| regulation of chromatin organization |
| meiotic cell cycle |
| germ cell development |
| sex differentiation |
| nuclear division |
| organelle fission |
| regulation of chromosome organization |
| cellular process involved in reproduction in multicellular organism |
| sequence-specific DNA binding |
| cellular component |
| spermatogenesis |
| male gamete generation |
| positive regulation of organelle organization |
| developmental process involved in reproduction |
| gamete generation |
| molecular function |
| multicellular organismal reproductive process |
| sexual reproduction |
| multicellular organism reproduction |
| protein homodimerization activity |
| multi-organism reproductive process |
| cell cycle process |
| positive regulation of cellular component organization |
| positive regulation of protein modification process |
| regulation of organelle organization |
| cell cycle |
| reproductive process |
| reproduction |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of cellular protein metabolic process |
| cell development |
| positive regulation of protein metabolic process |
| regulation of protein modification process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 1/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution