DNAJB5
Gene Information
- Official Symbol: DNAJB5
- Official Name: DnaJ heat shock protein family (Hsp40) member B5
- Aliases and Previous Symbols: N/A
- Entrez ID: 25822
- UniProt: O75953
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy. [provided by RefSeq, Mar 2017].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5873
- Expression level (log2 read counts): 2.67
DNAJB5 Expression in NALM6 Cells: 2.67
