UniProt Summary: Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism. {ECO:0000269|PubMed:9632644}.
Pfam DomainsGO Terms
Pfam Domains
Peptidase M18
GO Terms
metalloaminopeptidase activity
aminopeptidase activity
blood microparticle
peptide metabolic process
cellular amide metabolic process
zinc ion binding
identical protein binding
proteolysis
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739