EFEMP2
Gene Information
- Official Symbol: EFEMP2
- Official Name: EGF containing fibulin extracellular matrix protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 30008
- UniProt: O95967
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8968
- Expression level (log2 read counts): -0.25
EFEMP2 Expression in NALM6 Cells: -0.25
