UniProt Summary: May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA. {ECO:0000250, ECO:0000269|PubMed:10710437, ECO:0000269|PubMed:7898713}.
Pfam DomainsGO Terms
Pfam Domains
RRM 1
GO Terms
mRNA 3-UTR AU-rich region binding
mRNA 3-UTR binding
mRNA processing
mRNA metabolic process
RNA processing
RNA metabolic process
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739