Entrez Summary: The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
FERM C
FA
FERM M
FERM N
GO Terms
cytoskeletal protein binding
actomyosin structure organization
cytoskeleton
cellular component
actin cytoskeleton organization
actin filament-based process
molecular function
cytoskeleton organization
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739