UniProt Summary: Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde. {ECO:0000269|PubMed:22241472}.
Pfam DomainsGO Terms
Pfam Domains
Aminotran 3
GO Terms
ethanolamine-phosphate phospho-lyase activity
transaminase activity
phosphatidylethanolamine biosynthetic process
phosphatidylethanolamine metabolic process
pyridoxal phosphate binding
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
glycerophospholipid metabolic process
mitochondrial matrix
phospholipid metabolic process
glycerolipid metabolic process
cellular component
organophosphate biosynthetic process
lipid biosynthetic process
organophosphate metabolic process
cellular lipid metabolic process
lipid metabolic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739