UniProt Summary: Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. {ECO:0000269|PubMed:17492404, ECO:0000269|PubMed:19029833}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
autophagy
process utilizing autophagic mechanism
lysosomal membrane
endoplasmic reticulum lumen
post-translational protein modification
intracellular membrane-bounded organelle
apoptotic process
endoplasmic reticulum membrane
programmed cell death
cell death
cellular catabolic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)