UniProt Summary: Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli. {ECO:0000269|PubMed:21339736}.
Pfam DomainsGO Terms
Pfam Domains
DUF1754
GO Terms
nucleolus
apoptotic process
programmed cell death
cell death
cell cycle
RNA binding
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)