FGFBP3
Gene Information
- Official Symbol: FGFBP3
- Official Name: fibroblast growth factor binding protein 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 143282
- UniProt: Q8TAT2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability. {ECO:0000269|PubMed:18669637}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15025
- Expression level (log2 read counts): 3.89
FGFBP3 Expression in NALM6 Cells: 3.89
