FUOM
Gene Information
- Official Symbol: FUOM
- Official Name: fucose mutarotase
- Aliases and Previous Symbols: N/A
- Entrez ID: 282969
- UniProt: A2VDF0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Involved in the interconversion between alpha- and beta- L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O- glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. {ECO:0000269|PubMed:17602138}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16756
- Expression level (log2 read counts): 2.33
FUOM Expression in NALM6 Cells: 2.33
