GC
Gene Information
- Official Symbol: GC
- Official Name: GC vitamin D binding protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 2638
- UniProt: P02774
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
- UniProt Summary: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. {ECO:0000305|PubMed:16302727}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17745
- Expression level (log2 read counts): -7.68
GC Expression in NALM6 Cells: -7.68
