UniProt Summary: Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production. {ECO:0000250|UniProtKB:Q80WT4}.
Pfam DomainsGO Terms
Pfam Domains
7tm 1
GO Terms
circadian behavior
rhythmic behavior
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
circadian rhythm
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
rhythmic process
chemical synaptic transmission
anterograde trans-synaptic signaling
trans-synaptic signaling
synaptic signaling
behavior
G protein-coupled receptor activity
cell-cell signaling
G protein-coupled receptor signaling pathway
integral component of plasma membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)