GPR88
Gene Information
- Official Symbol: GPR88
- Official Name: G protein-coupled receptor 88
- Aliases and Previous Symbols: N/A
- Entrez ID: 54112
- UniProt: Q9GZN0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a G protein-coupled receptor found almost exclusively in the striatum, a brain structure that controls motor function and cognition. Defects in this gene have been associated with chorea, speech delay, and learning difficulties, as well as some neuropsychiatric disorders. [provided by RefSeq, Mar 2017].
- UniProt Summary: Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function. {ECO:0000250|UniProtKB:Q9EPB7, ECO:0000250|UniProtKB:Q9ESP4}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6123
- Expression level (log2 read counts): -4.27
GPR88 Expression in NALM6 Cells: -4.27
