GRK4
Gene Information
- Official Symbol: GRK4
- Official Name: G protein-coupled receptor kinase 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 2868
- UniProt: P32298
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11049
- Expression level (log2 read counts): 3.02
GRK4 Expression in NALM6 Cells: 3.02
