HTR3C
Gene Information
- Official Symbol: HTR3C
- Official Name: 5-hydroxytryptamine receptor 3C
- Aliases and Previous Symbols: N/A
- Entrez ID: 170572
- UniProt: Q8WXA8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008].
- UniProt Summary: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14485
- Expression level (log2 read counts): -7.68
HTR3C Expression in NALM6 Cells: -7.68
