IL20RB
Gene Information
- Official Symbol: IL20RB
- Official Name: interleukin 20 receptor subunit beta
- Aliases and Previous Symbols: N/A
- Entrez ID: 53833
- UniProt: Q6UXL0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Pfam Domains GO Terms
Pfam Domains
| Interfer-bind |
| Tissue fac |
GO Terms
| negative regulation of type IV hypersensitivity |
| negative regulation of hypersensitivity |
| regulation of type IV hypersensitivity |
| interleukin-20 binding |
| negative regulation of acute inflammatory response to antigenic stimulus |
| immune response-inhibiting signal transduction |
| regulation of hypersensitivity |
| negative regulation of acute inflammatory response |
| negative regulation of inflammatory response to antigenic stimulus |
| regulation of acute inflammatory response to antigenic stimulus |
| negative regulation of T cell mediated immunity |
| negative regulation of interleukin-2 production |
| positive regulation of interleukin-4 production |
| inflammatory response to antigenic stimulus |
| regulation of inflammatory response to antigenic stimulus |
| regulation of interleukin-4 production |
| homeostasis of number of cells within a tissue |
| negative regulation of interferon-gamma production |
| positive regulation of interleukin-10 production |
| negative regulation of lymphocyte mediated immunity |
| negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
| regulation of acute inflammatory response |
| negative regulation of adaptive immune response |
| cytokine receptor activity |
| negative regulation of leukocyte mediated immunity |
| regulation of interleukin-10 production |
| regulation of interleukin-2 production |
| negative regulation of T cell proliferation |
| regulation of T cell mediated immunity |
| negative regulation of lymphocyte proliferation |
| negative regulation of mononuclear cell proliferation |
| negative regulation of leukocyte proliferation |
| regulation of interferon-gamma production |
| negative regulation of T cell activation |
| negative regulation of immune effector process |
| negative regulation of leukocyte cell-cell adhesion |
| negative regulation of inflammatory response |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
| negative regulation of lymphocyte activation |
| negative regulation of immune response |
| regulation of lymphocyte mediated immunity |
| regulation of T cell proliferation |
| regulation of adaptive immune response |
| negative regulation of leukocyte activation |
| negative regulation of cell-cell adhesion |
| tissue homeostasis |
| negative regulation of cell activation |
| homeostasis of number of cells |
| regulation of leukocyte mediated immunity |
| negative regulation of defense response |
| regulation of lymphocyte proliferation |
| regulation of mononuclear cell proliferation |
| regulation of leukocyte proliferation |
| negative regulation of cell adhesion |
| negative regulation of cytokine production |
| regulation of leukocyte cell-cell adhesion |
| regulation of T cell activation |
| multicellular organismal homeostasis |
| regulation of inflammatory response |
| anatomical structure homeostasis |
| negative regulation of response to external stimulus |
| regulation of cell-cell adhesion |
| negative regulation of immune system process |
| positive regulation of cytokine production |
| regulation of immune effector process |
| inflammatory response |
| regulation of lymphocyte activation |
| immune response-regulating signaling pathway |
| regulation of leukocyte activation |
| regulation of cell activation |
| cytokine-mediated signaling pathway |
| negative regulation of cell population proliferation |
| regulation of cell adhesion |
| regulation of cytokine production |
| regulation of defense response |
| cellular response to cytokine stimulus |
| regulation of response to external stimulus |
| response to cytokine |
| regulation of immune response |
| negative regulation of multicellular organismal process |
| defense response |
| regulation of response to stress |
| regulation of cell population proliferation |
| negative regulation of response to stimulus |
| homeostatic process |
| regulation of immune system process |
| positive regulation of multicellular organismal process |
| immune response |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12692
- Expression level (log2 read counts): 0.83
Expression Distribution
IL20RB Expression in NALM6 Cells: 0.83
