INA
Gene Information
- Official Symbol: INA
- Official Name: internexin neuronal intermediate filament protein alpha
- Aliases and Previous Symbols: N/A
- Entrez ID: 9118
- UniProt: Q16352
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009].
- UniProt Summary: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 4516
- Expression level (log2 read counts): 2.59
INA Expression in NALM6 Cells: 2.59
