ITIH5

• Official Symbol: ITIH5
• Official Name: inter-alpha-trypsin inhibitor heavy chain 5
• Aliases and Previous Symbols: N/A
• Entrez ID: 80760
• UniProt: Q86UX2
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 15393
• Expression level (log2 read counts): 3.81

Expression Distribution

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ITIH5 Expression in NALM6 Cells: 3.81